The spectacular development of medical knowledge over the last two centuries has brought intrusive advances in the capabilities of medical technology. These advances have been remarkable over the last century, but especially over the last few decades, culminating in such high technology interventions as heart transplants and renal dialysis. These increases in medical powers have attracted societal interest in acquiring more such knowledge. They have also spawned concerns regarding the use of human subjects in research and regarding the byproducts of (...) basic research as in the recent recombinant DNA debate. As a consequence of the development of new biomedical knowledge, physicians and biomedical scientists have been placed in positions of new power and responsibility. The emergence of this group of powerful and knowledgeable experts has occasioned debates regarding the accountability of physicians and biomedical scientists. But beyond that, the very investment of resources in the acquisition of new knowledge has been questioned. Societies must decide whether finite resources would not be better invested at this juncture, or in general, in the alleviation of the problems of hunger or in raising general health standards through interventions which are less dependent on the intensive use of high technology. To put issues in this fashion touches on philosophical notions concerning the claims of distributive justice and the ownership of biomedical knowledge. (shrink)

The epithet χαλκοκραυνον has perturbed many, though the most recent English editors have printed it without comment. The new Liddell and Scott betrays uneasiness in its ‘epithet of the sea, perhaps false reading for χαλκαμρυγος, gleaming like copper or bronze’. Overseas scholars flatly reject it. Wilamowitz poured scorn on it in his Interpretationen and commented in his larger edition neque intelligitur et frustra temptatum est. Weir Smyth obelizes it. Bothe, Hermann, Weil, and others offered emendations. In Bursians Jahresberichte, ccxxxiv, (...) p. 104 W. Morel observed Von Erz und Blitz befreit uns Bruhns χλιαρκρουνον. This is emancipation indeed. (shrink)

The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into (...) two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topics on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summarizes discussion and conclusions from the workshop. (shrink)

West takes his title from Camus, and quotes Camus' definition of absurdity: "the division between the mind that desires and the world that disappoints." The essays, which originally appeared in periodicals, discuss Yeats, Lawrence, Sartre, Camus, Simon Weil, Graham Greene, Santayana, and other modern writers. There is no analysis, either philosophical or literary; West attempts overall estimates of each writer's contribution to the problem of absurdity, but succeeds in providing neither insights for those already familiar with the problem nor (...) useful introductions for the uninitiated. Nor, despite the expectations aroused by the preface, do we get a very strong impression of an individual's encounter with the thinkers from whom he has learned most. In vino vacuitas.—W. B. K. (shrink)

West takes his title from Camus, and quotes Camus' definition of absurdity: "the division between the mind that desires and the world that disappoints." The essays, which originally appeared in periodicals, discuss Yeats, Lawrence, Sartre, Camus, Simon Weil, Graham Greene, Santayana, and other modern writers. There is no analysis, either philosophical or literary; West attempts overall estimates of each writer's contribution to the problem of absurdity, but succeeds in providing neither insights for those already familiar with the problem nor (...) useful introductions for the uninitiated. Nor, despite the expectations aroused by the preface, do we get a very strong impression of an individual's encounter with the thinkers from whom he has learned most. In vino vacuitas.—W. B. K. (shrink)

Psychologists' emerging interest in spirituality and religion as well as the relevance of each phenomenon to issues of psychological importance requires an understanding of the fundamental characteristics of each construct. On the basis of both historical considerations and a limited but growing empirical literature, we caution against viewing spirituality and religiousness as incompatible and suggest that the common tendency to polarize the terms simply as individual vs. institutional or ′good′ vs. ′bad′ is not fruitful for future research. Also cautioning against (...) the use of restrictive, narrow definitions or overly broad definitions that can rob either construct of its distinctive characteristics, we propose a set of criteria that recognizes the constructs' conceptual similarities and dissimilarities. Rather than trying to force new and likely unsuccessful definitions, we offer these criteria as benchmarks for judging the value of existing definitions. (shrink)

W. E. B. Du Bois was a public intellectual, sociologist, and activist on behalf of the African American community. He profoundly shaped black political culture in the United States through his founding role in the NAACP, as well as internationally through the Pan-African movement. Du Bois's sociological and historical research on African-American communities and culture broke ground in many areas, including the history of the post-Civil War Reconstruction period. Du Bois was also a prolific author of novels, autobiographical accounts, innumerable (...) editorials and journalistic pieces, and several works of history. Collected in one volume for the first time, The World and Africa and Color and Democracy are two of W E. B. Du Bois's most powerful essays on race. He explores how to tell the story of those left out of recorded history, the evils of colonialism worldwide, and Africa's and African's contributions to, and neglect from, world history. More than six decades after W. E. B. Du Bois wrote The World and Africa and Color and Democracy, they remain worthy guides for the twenty-first century. With a series introduction by editor Henry Louis Gates, Jr., and two introductions by top African scholars, this edition is essential for anyone interested in world history. (shrink)

This is the first book to offer the best essays, articles, and speeches on ethics and intelligence that demonstrate the complex moral dilemmas in intelligence collection, analysis, and operations. Some are recently declassified and never before published, and all are written by authors whose backgrounds are as varied as their insights, including Robert M. Gates, former Director of the Central Intelligence Agency; John P. Langan, the Joseph Cardinal Bernardin Professor of Catholic Social Thought at the Kennedy Institute of Ethics, Georgetown (...) University; and Loch K. Johnson, Regents Professor of Political Science at the University of Georgia and recipient of the Owens Award for contributions to the understanding of U.S. intelligence activities. Creating the foundation for the study of ethics and intelligence by filling in the gap between warfare and philosophy, this is a valuable collection of literature for building an ethical code that is not dependent on any specific agency, department, or country. (shrink)

Recent reports of the discovery of a “God module” in the human brain derive from the fact that epileptic seizures in the left temporal lobe are associated with ecstatic feelings sometimes described as an experience of the presence of God. The brain area involved has been described as either (a) the seat of an innate human faculty for experiencing the divine or (b) the seat of religious delusions.In fact, religious experience is extremely various and involves many parts of the brain, (...) including some that are prehuman in their evolutionary history and some that are characteristically human. In the continuing integration of such experiences, spiritual formation takes place. Thus the entire human brain might be described as a “God module.”Such a process is only possible because of the brain's complexity. The human brain is the most complex entity for its size that we know of. As used here, complexity is a specialized term denoting the presence of a web of interlinked and significant connections—the more intricate the web, the more complex the entity. Complex systems develop only in a milieu that provides both lawfulness and freedom, and they tend to be self‐organizing, becoming more complex and more effective as a result of both inward and outward experience. The evidence suggests that both personal growth and spiritual growth are processes of complexification of character, and of the brain itself. This thesis is tested in light of the work of William James and James W. Fowler. (shrink)

"First published by Oxford University Press, 1916."--Title page verso.

The systematic study of supermatrices and super linear algebra has been carried out in 2008. These new algebraic structures find their applications in fuzzy models, Leontief economic models and data-storage in computers.

Principled discussions of civil rights became inherently less likely as a direct result of the observation by Earl Warren, in Brown v. Board of Education, that, respecting freedmen, “Education of Negroes was almost non-existent, and practically all of the race were illiterate,” and in proportion as that observation increasingly became the foundation of common opinion on the subject. Warren's observation was not true in any meaningful or non-trivial sense. Nevertheless, it served to perpetuate the myth of a backward people needing (...) help to catch up instead of the truth of a people being held back. That is the perspective – the disadvantaged group perspective – that ultimately infected all discussion of civil rights, even after the designation of so-called “disadvantaged groups” had been extended beyond American blacks. To define civil rights, we may well begin with what all mankind would likely recognize. Thus the dictionary definition of “civil rights” stands: “the rights that belong to all individuals in a nation or community touching property, marriage, and the like.” In that definition the term “rights” may be further expanded to mean “legitimate claims,” following the definition of right as law – as “a claim or title or interest in anything whatever that is enforceable by law.” This definition applies with minimal distinction of regimes intruding and, therefore, without the host of recent complications in the United States that create the impression that civil rights have something to do with pluralism. Previously, the generic definition was thought to exhaust the meaning of the term in the United States. (shrink)

"Bibliographical notes": pages [243]-244.

Everyone knows the statement of Servius that Virgil was compelled by Augustus to alter the second half of the Fourth Georgic after the fall of Gallus, and that he substituted the story of Aristaeus for the laudes Galli. This statement, often doubted by older generations, has had such a remarkable success in recent years that anyone who ventures to impugn it must feel that he is pleading with a halter round his neck before a one-sided jury. It is notable, however, (...) that these jurors, though one-sided, are by no means united, save in their determination to uphold the credit of Servius. One group will assure us that the episode of Aristaeus shows obvious signs not only of haste but of immaturity, and they draw a pathetic picture of the grief-stricken Virgil, ordered to bring out a second edition minus the praises of his friend Gallus, and half-heartedly throwing together some bits of juvenile stuff which he happened to have handy. Others assure us that the tale of Aristaeus shows us a more mature Virgil, nearer to the Virgil of the Aeneid. But the Servians really cannot have it both ways. They must make up their minds in the one direction or in the other if they are to be taken seriously. They make it doubly difficult for us to take them seriously when they try to tell us what Servius meant—but of that more anon. The present paper is an attempt by a converted Servian to examine frankly the arguments which have been advanced in support of Servius. Most of these may be found in Skutsch, Aus Vergils Frühzeit, pp. 140–147. One is very reluctant to use disparaging words about an eminent scholar who has served the cause of learning in so many ways; but it can scarcely be denied that the work just mentioned, in spite of its ingenuity and enthusiasm, shows a lamentable lack of three great essentials—a judicial temper, accurate statement of facts, and cogent reasoning. There is also at times a regrettable vagueness of expression, suggesting that the author is concealing inward doubts or shrinking from thought. All these deficiencies are to some extent present in the section with which this paper is concerned. (shrink)

© 2015 Elsevier Inc.Postnatal organogenesis occurs in an immune competent environment and is tightly controlled by interplay between positive and negative regulators. Innate immune cells have beneficial roles in postnatal tissue remodeling, but roles for the adaptive immune system are currently unexplored. Here we show that adaptive immune responses participate in the normal postnatal development of a non-lymphoid epithelial tissue. Since the mammary gland is the only organ developing predominantly after birth, we utilized it as a powerful system to study (...) adaptive immune regulation of organogenesis. We found that antigen-mediated interactions between mammary antigen-presenting cells and interferon-γ -producing CD4+ T helper 1 cells participate in MG postnatal organogenesis as negative regulators, locally orchestrating epithelial rearrangement. IFNγ then affects luminal lineage differentiation. This function of adaptive immune responses, regulating normal development, changes the paradigm for studying players of postnatal organogenesis and provides insights into immune surveillance and cancer transformation. Plaks et al. (shrink)